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NVIDIA RTX 4080 (16GB)

The NVIDIA RTX 4080 (16GB) features 16 GB of dedicated VRAM and 717 GB/s memory bandwidth, supporting CUDA and TensorRT-LLM runtimes for full-precision and quantized inference.

Memory

16 GB

Usable Memory Ceiling

16 GB

Bandwidth

716.8 GB/s

Max Inference Class

14B Models (Q4)

TDP

320W

VRAM Scaling by Context Length

Estimated memory requirements as context length increases. Curves crossing above the reference line indicate Out of Memory (OOM).

Gemma 3 270M (0.27B)ChatGLM-6B (6B)Gemma 3 12B (12B)Mixtral-8x7B-v0.1 (46.7B (7B active))

Precision:

Best Models to Run on NVIDIA RTX 4080 (16GB)

Inference throughput, memory compatibility, and generation speeds for open-weights LLMs on NVIDIA RTX 4080 (16GB).

Sort by:

Context:

KV Cache:

GPUs:

RankModelParametersPrecisionTPS (Approx.)TTFTCan Run

#33

Qwen 3.8 27B

27B

INT4

32 tok/s

~1.8s

#83

Qwen3.5-27B

27B

INT4

32 tok/s

~1.8s

#100

Phi-4 Reasoning Plus

14B

INT4

47 tok/s

~815 ms

#101

MiMo V2 Flash

15B (309B active)

INT4

3 tok/s

~18.1s

#108

Gemma 4 26B A4B

25.2B (3.8B active)

INT4

132 tok/s

~303 ms

#109

Gemma 4 12B

11.95B

INT4
Q8

53 tok/s

33 tok/s

~699 ms

~829 ms

#113

Qwen3.5-9B

9B

INT4
Q8

89 tok/s

56 tok/s

~527 ms

~534 ms

#118

K2 Horizon 7B

7B

INT4
Q8
FP16

106 tok/s

68 tok/s

34 tok/s

~414 ms

~419 ms

~503 ms

#128

NVIDIA Nemotron 3 Nano 30B-A3B

3.5B (30B active)

INT4
Q8
FP16

31 tok/s

18 tok/s

10 tok/s

~1.6s

~1.7s

~1.7s

#132

Qwen3.5-4B

4B

INT4
Q8
FP16

151 tok/s

104 tok/s

62 tok/s

~245 ms

~248 ms

~255 ms

#136

GPT-OSS 20B

21B (3.6B active)

INT4

65 tok/s

~314 ms

#146

Granite 4.2 8B

8B

INT4
Q8

97 tok/s

61 tok/s

~470 ms

~476 ms

#150

Gemma 4 E4B

8B

INT4
Q8

97 tok/s

61 tok/s

~470 ms

~476 ms

#158

GLM-4V

9B

INT4
Q8

66 tok/s

44 tok/s

~531 ms

~582 ms

#159

Gemma 3 27B

27B

INT4

32 tok/s

~1.8s

#160

Phi-4

14B

INT4
Q8

63 tok/s

34 tok/s

~810 ms

~961 ms

#169

OLMo 3 7B Think

7B

INT4
Q8

78 tok/s

56 tok/s

~417 ms

~422 ms

#172

DeepSeek-R1 14B

14B

INT4
Q8

64 tok/s

35 tok/s

~809 ms

~960 ms

#173

Ministral 3 14B

14B

INT4

47 tok/s

~815 ms

#177

Gemma 3 12B

12B

INT4
Q8

71 tok/s

41 tok/s

~697 ms

~765 ms

Inference Capacity

Maximum model parameter class runnable by weight precision.

Context:

4-bit

Q4

14B Models

8-bit

Q8

8B Models

16-bit

FP16

3B Models

Fine-Tuning Capacity

Hardware capacity for local training and adapter fine-tuning.

Context Length:

QLoRA

4-bit

14B Models

LoRA

16-bit

8B Models

Full Parameter Training

1B Models

Workload Recommendations

Guidance for optimal precision and operational ceilings on NVIDIA RTX 4080 (16GB).

Inference Sweet Spot

Optimal for 8B models across extended context (32k+). 14B models fit comfortably at Q4 precision with standard context.

Bandwidth & Speed Profile

With 716.8 GB/s aggregate bandwidth, batch size 1 inference operates in a memory-bandwidth bound regime. Generates approximately 159 tok/s on an 8B Q4 model and 19 tok/s on a 70B Q4 model.

Frequently Asked Questions